NGS decreases labor intensive techniques in a microbiology laboratory using an all inclusive diagnostic test. NGS or Next Generation Sequencing, offers fast results in a variety of projects. While each laboratory is different, testing is basically the same. The platforms used to determine sequencing are either wet or dry laboratory analysis.
NGS Testing Projects
Whole genome sequencing creates a library of bacteria from people. Non-protein coding, or the sequencing of small nuclear RNA is another test performed using Next Generation Sequencing. Metagenomics for sequencing of environmental DNA used to compare gene samples through the sequencing of RNA extraction, and a number of other microbiological tests can be performed. After testing, library preparation, an analysis of the data results, and the extraction of the DNA are completed. Test results are often available in one day.
NGS Microbiological Tests in Infectious Diseases
Public health laboratories are utilizing rapid testing for diagnosing infectious diseases in hospitals and other medical facilities across the country. The benefits are great, although safety standards must be closely followed. Laboratories must be accredited and guidelines followed to ensure quality results. The CDC (Center for Disease Control) is working to implement Next Generation Sequencing in laboratories of public health facilities, as are the AMD (Advanced Molecular Detection), the FDC (Food and Drug Administration), and the NCBI (National Center for Biotechnology Information).
NGS Testing Improves Vaccines
The prevention of nationwide outbreaks of infectious diseases can be treated quickly using rapid Next Generation Sequencing. Rapid results offer chemists, doctors, and scientists the ability to track bacteria, whether they are airborne or food borne. The results are used to improve vaccines and identify threats to the public. They are also used to identify the resistance of a variety of medications used to treat diseases.